ASC0'22 Recommended Abstracts: DOWNLOAD PDF

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These recommended abstracts from ASCO22 Annual meeting have been selected by Robert A. Figlin, MD, Editor-in- Chief of the Kidney Cancer Journal. The chosen abstracts provided here highlight some of the most important trends in ongoing trials and reflect the foremost research and strategies from latest clinical trials that impact the current standard of care in renal cancer.

Abstract Titles

ABSTRACT LBA4500:

EVEREST: Everolimus for renal cancer ensuing surgical therapy—A phase III study (SWOG S0931, NCT01120249).

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  • ABSTRACT 4501:

    Association between depth of response (DepOR) and clinical outcomes: Exploratory analysis in patients with previously untreated advanced renal cell carcinoma (aRCC) in CheckMate 9ER.

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  • ABSTRACT 4502 :

    The relationship between health-related quality of life (HRQoL) and clinical outcomes in patients with advanced renal cell carcinoma (aRCC) in CheckMate (CM) 214.

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  • ABSTRACT LBA4503 :

    CALYPSO: A three-arm randomized phase II study of durvalumab alone or with savolitinib or tremelimumab in previously treated advanced clear cell renal cancer.

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  • ABSTRACT 4509:

    Phase 1 LITESPARK-001 (MK-6482-001) study of belzutifan in advanced solid tumors: Update of the clear cell renal cell carcinoma (ccRCC) cohort with more than 3 years of total follow-up.

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  • ABSTRACT 4511 :

    A phase 1b/2 study of batiraxcept (AVB-S6-500) in combination with cabozantinib in patients with advanced or metastatic clear cell renal cell (ccRCC) carcinoma who have received front-line treatment (NCT04300140).

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  • ABSTRACT 4512 :

    Adjuvant pembrolizumab for postnephrectomy renal cell carcinoma (RCC): Expanded efficacy analyses from KEYNOTE-564.

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  • ABSTRACT 4513 :

    Pembrolizumab (pembro) plus axitinib (axi) versus sunitinib as first-line therapy for advanced clear cell renal cell carcinoma (ccRCC): Analysis of progression after first subsequent therapy in KEYNOTE-426.

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  • ABSTRACT 4514 :

    Impact of subsequent therapies in patients (pts) with advanced renal cell carcinoma (aRCC) receiving lenvatinib plus pembrolizumab (LEN + PEMBRO) or sunitinib (SUN) in the CLEAR study.

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    ABSTRACT LBA4500:

  • ASCO Link - https://meetings.asco.org/abstracts-presentations/207883
  • EVEREST: Everolimus for renal cancer ensuing surgical therapy—A phase III study (SWOG S0931, NCT01120249)..

  • Citation: J Clin Oncol 40, 2022 (suppl 17; abstr LBA4500)

    ABSTRACT 4501:

  • ASCO Link - https://meetings.asco.org/abstracts-presentations/207895
  • Association between depth of response (DepOR) and clinical outcomes: Exploratory analysis in patients with previously untreated advanced renal cell carcinoma (aRCC) in CheckMate 9ER.

  • Citation: J Clin Oncol 40, 2022 (suppl 16; abstr 4501)

    ABSTRACT 4501 :

  • ASCO Link - https://meetinglibrary.asco.org/record/205607/abstract
  • Characterizing IMDC prognostic groups in contemporary first-line combination therapies for metastatic renal cell carcinoma (mRCC).

    ABSTRACT 4502 :

  • ASCO Link - https://meetings.asco.org/abstracts-presentations/207896
  • The relationship between health-related quality of life (HRQoL) and clinical outcomes in patients with advanced renal cell carcinoma (aRCC) in CheckMate (CM) 214.

  • DOI: 10.1200/JCO.2022.40.16_suppl.4502

    ABSTRACT LBA4503 :

  • ASCO Link - https://meetings.asco.org/abstracts-presentations/209130
  • CALYPSO: A three-arm randomized phase II study of durvalumab alone or with savolitinib or tremelimumab in previously treated advanced clear cell renal cancer.

    ABSTRACT 4509:

  • ASCO Link - https://meetings.asco.org/abstracts-presentations/207892
  • Phase 1 LITESPARK-001 (MK-6482-001) study of belzutifan in advanced solid tumors: Update of the clear cell renal cell carcinoma (ccRCC) cohort with more than 3 years of total follow-up. Add to Collection

  • DOI: 10.1200/JCO.2022.40.16_suppl.4509

    ABSTRACT 4511 :

  • ASCO Link - https://meetings.asco.org/abstracts-presentations/207886
  • A phase 1b/2 study of batiraxcept (AVB-S6-500) in combination with cabozantinib in patients with advanced or metastatic clear cell renal cell (ccRCC) carcinoma who have received front-line treatment (NCT04300140).

  • DOI: 10.1200/JCO.2022.40.16_suppl.4511

    ABSTRACT 4512 :

  • ASCO Link - https://meetings.asco.org/abstracts-presentations/207894
  • DOI: 10.1200/JCO.2022.40.16_suppl.4513

    Adjuvant pembrolizumab for postnephrectomy renal cell carcinoma (RCC): Expanded efficacy analyses from KEYNOTE-564.

  • DOI: 10.1200/JCO.2022.40.16_suppl.4512

    ABSTRACT 4513 :

  • ASCO Link - https://meetings.asco.org/abstracts-presentations/207891
  • Pembrolizumab (pembro) plus axitinib (axi) versus sunitinib as first-line therapy for advanced clear cell renal cell carcinoma (ccRCC): Analysis of progression after first subsequent therapy in KEYNOTE-426.

  • DOI: 10.1200/JCO.2022.40.16_suppl.4513

    ABSTRACT 4514 :

  • ASCO Link - https://meetings.asco.org/abstracts-presentations/209127
  • Impact of subsequent therapies in patients (pts) with advanced renal cell carcinoma (aRCC) receiving lenvatinib plus pembrolizumab (LEN + PEMBRO) or sunitinib (SUN) in the CLEAR study.

  • DOI: 10.1200/JCO.2022.40.16_suppl.4514